abstract：:During syngeneic pregnancy the numbers of 'spontaneously' occurring ('background') Ig-secreting cells were determined in the spleen, bone marrow (BM) and mesenteric lymph nodes (MLN) of BALB/c mice that were kept under germfree conditions and fed a low molecular weight synthetic diet (GF-CD), SPF BALB/c mice fed autoc...

journal_title：Journal of reproductive immunology

authors： Bos NA,Benner R,Wostmann BS,Pleasants JR

更新日期：1986-11-01 00:00:00

abstract：:The isolation and partial characterization of an immunosuppressive early pregnancy factor (EPF) present in the serum of pregnant women, between 3 and 8 weeks of gestation, is described. EPF was purified using ion-exchange chromatography, affinity chromatography and HPLC gel permeation techniques. A homogeneous, active...

journal_title：Journal of reproductive immunology

authors： Mehta AR,Moodbidri SB,Raghavan VP,Shahani SK

更新日期：1986-11-01 00:00:00

abstract：:A comparative study on anti-zona antibody activities in the sera from clinically defined categories of patients registered at the WHO Reference Bank for Reproductive Immunology was performed at five different laboratories with different detection methods. Considerably higher incidences of positive reactions were detec...

journal_title：Journal of reproductive immunology

authors： Mori T,Kamada M,Hasebe H,Irahara M,Shivers A,Czuppon AB,Mettler L,Mathur S,Dunbar BS

更新日期：1985-12-01 00:00:00

abstract：:Various ELISA methods have been applied by different research centers to test the efficiency of this approach for the diagnosis of sperm-immune infertility cases. The antigens used were either whole spermatozoa or solubilized spermatozoal membrane preparations and were immobilized on microtiter plates, except in one c...

journal_title：Journal of reproductive immunology

authors： Mettler L,Czuppon AB,Alexander N,D'Almeida M,Haas GG Jr,Hjort T,Møller Jensen J,Ing R,Jones WR,Wang SX

更新日期：1985-12-01 00:00:00

abstract：:Inbred mice from selected unrelated and congenic strains were mated to determine the relative effects of maternal-fetal disparity at major histocompatibility complex (H-2) and non-H-2 minor histocompatibility antigens on the feto-placental unit at 14 days of gestation. A significant increase in weight of the feto-plac...

journal_title：Journal of reproductive immunology

authors： Hamilton BL,Hamilton A,Hamilton MS

更新日期：1985-11-01 00:00:00

abstract：:Alloreactive T levels of para-aortic lymph nodes (PALN) and spleen were determined on different days of pregnancy in BALB/c females by local and systemic graft-versus-host (GvH) assays. A significant increase in GvH reactivity was registered early in both allogeneic and syngeneic matings, operating not only towards pa...

journal_title：Journal of reproductive immunology

authors： Piazzón I,Matusevich M,Déroche A,Nepomnaschy I,Pasqualini CD

更新日期：1985-11-01 00:00:00

abstract：:The effect of human seminal plasma on the natural killer (NK) activity of human peripheral blood leukocytes in vitro has been investigated. Small concentrations (as low as 0.01% v/v) of seminal plasma were found to inhibit the ability of human peripheral blood leukocytes to lyse K562 target cells. These inhibitory eff...

journal_title：Journal of reproductive immunology

authors： James K,Szymaniec S

更新日期：1985-08-01 00:00:00

abstract：:Published data on progeny sex ratio changes resulting from induction or administration of anti-male antibody in parental generation were compared by Fisher's independent test of significance. Sex ratio (males/total) depression is highly significant (P less than 0.001). Our large sample size data confirm this result; s...

journal_title：Journal of reproductive immunology

authors： Pechan P

更新日期：1985-06-01 00:00:00

abstract：:Autologous anti-horseradish peroxidase antibody has been localized in pregnant rats at various levels through placental membranes en passage to fetal circulation. The antibody was complexed in situ with the antigen and the resulting complex was made visible electron microscopically by immunohistochemical techniques. V...

journal_title：Journal of reproductive immunology

authors： Jollie WP

更新日期：1985-05-01 00:00:00

abstract：:The immune reactivity of lymphoid cells from pregnant mice was studied during the course of pregnancy in primiparous and multiparous animals either " isopregnant " (male and female of same strain) or " allopregnant " (male and female differing at H-2), using a local GVH assay (CBA lymphoid cells injected into (CBA X A...

journal_title：Journal of reproductive immunology

authors： Dorić M,Kinsky RG,Voisin GA

更新日期：1984-05-01 00:00:00

abstract：:The rabbit sperm membrane autoantigen, RSA-1, has been isolated from the kidneys of bilaterally vasectomized rabbits. Using detergent extraction the IgG-RSA-1 complex in the kidney was isolated first on an anti-IgG immunocolumn. The eluted IgG-RSA-1 complex was then applied to an anti-sperm autoantibody column which b...

journal_title：Journal of reproductive immunology

authors： O'Rand MG,Porter JP,Alexander NJ

更新日期：1984-02-01 00:00:00

abstract：:The mixed lymphocyte culture (MLC) of maternal and newborn (cord) cells is significantly weaker than that of father-newborn and control-newborn cultures. This hyporeactivity was found not to be due to an impaired function or tolerance of either the maternal or neonatal cells. We investigated the possibility that a spe...

journal_title：Journal of reproductive immunology

authors： Stankova J,Rola-Pleszczynski M

更新日期：1984-01-01 00:00:00

abstract：:This study showed that there are relationships between thymic and adrenal/ovarian endocrine actions. A 4 mg/kg dose of thymosin fraction 5 (TSN5) advanced vaginal opening and elevated estrogen levels. Single estradiol benzoate (EB) injections decreased thymus weight and caused a transient reduction in circulating plas...

journal_title：Journal of reproductive immunology

authors： Allen LS,McClure JE,Goldstein AL,Barkley MS,Michael SD

更新日期：1984-01-01 00:00:00

abstract：:Human trophoblast membrane antigens recognised by monoclonal antibodies (H310, H315, H316 and H317) have been identified using combinations of radioimmunoprecipitation, SDS-PAGE, electroblotting, chromatographic and ELISA-type techniques. H317 is known to identify heat-stable placental-type alkaline phosphatase and ac...

journal_title：Journal of reproductive immunology

authors： Brown PJ,Molloy CM,Johnson PM

更新日期：1983-11-01 00:00:00

abstract：:A large number of cells in the first trimester human placenta have been shown to express leucocyte-common antigen by the use of a monoclonal antibody in an immunoperoxidase technique. The distribution of endometrial granulocytes in the decidua of early pregnancy indicates that a large proportion of these cells bear th...

journal_title：Journal of reproductive immunology

authors： Bulmer JN,Sunderland CA

更新日期：1983-11-01 00:00:00

abstract：:Progesterone and glucocorticoids share important anti-inflammatory and immunosuppressive properties. Both hormones have potent anti-proliferative effects in MLR, mitogen activation and cytotoxic T-cell generation. We investigated the cellular target of this in vitro anti-proliferative activity by comparing the effects...

journal_title：Journal of reproductive immunology

authors： Stites DP,Bugbee S,Siiteri PK

更新日期：1983-07-01 00:00:00

abstract：:63 female rhesus monkeys were actively immunized against the beta-subunit of ovine luteinizing hormone (oLH beta). 75% of these monkeys developed antibodies which were sufficiently high to induce infertility. We report here the in vivo neutralizing potencies of anti-oLH beta antisera from 14 monkeys and the correlatio...

journal_title：Journal of reproductive immunology

authors： Yamamoto Y,Thau RB

更新日期：1983-07-01 00:00:00

abstract：:A rat monoclonal antibody (5D4) apparently specific for murine embryonal carcinoma cells and cells of the pre-implantation embryo is described. It does not react with differentiated cells from a variety of different tumours and tissues of the mouse. Biochemical studies show that the molecules that carry 5D4 antigen ar...

journal_title：Journal of reproductive immunology

authors： Stern PL,Gilbert P,Heath JK,Furth M

更新日期：1983-05-01 00:00:00

abstract：:An iso-antigen has been isolated from tritium-labelled human spermatozoa by detergent solubilization, lectin affinity chromatography and indirect immunoprecipitation using human iso-antisera. Isolated material was characterized by SDS-polyacrylamide gel electrophoresis. With these iso-antisera it was possible to isola...

journal_title：Journal of reproductive immunology

authors： Poulsen F

更新日期：1983-01-01 00:00:00

abstract：:The rosette inhibition test for the detection of early pregnancy factor is described in detail. The extended methodology presented here represents the cumulative experience of three independent laboratories. Special reference is made to the effect on the assay of varying the conditions of rosette formation between lym...

journal_title：Journal of reproductive immunology

authors： Morton H,Tinneberg HR,Rolfe B,Wolf M,Mettler L

更新日期：1982-09-01 00:00:00

abstract：:A quantitative immunohistochemical study of IgA-containing plasma cells in the human uterine cervix has shown that the number of such cells increases during the late secretory phase of the menstrual cycle but decreases in the early secretory phase of the cycle, in pregnancy, in cystic glandular hyperplasia of the endo...

journal_title：Journal of reproductive immunology

authors： Murdoch AJ,Buckley CH,Fox H

更新日期：1982-02-01 00:00:00

abstract：:C57BL/6 inbred female mice preimmunized by serial injections of isogeneic male spleen cells were mated and the effects of the circulating anti H-Y antibodies on the fetal gonads and on their fertility were studied. Female mice receiving injections of saline formed one control group and those given female spleen cells ...

journal_title：Journal of reproductive immunology

authors： Rao CS,Vaidya RA,Ambani LM

更新日期：1981-07-01 00:00:00

abstract：:Lymphocytes in human colostrum were examined for evidence of alloreactivity specifically directed against the paternal HLA haplotype. Such reactivity was detected using umbilical cord blood leukocytes as stimulator cells in the mixed lymphocyte reaction, but the responses were reduced when compared to those of the sam...

journal_title：Journal of reproductive immunology

authors： Parmely MJ,Williams SB

更新日期：1981-06-01 00:00:00

abstract：:The structure of a high-molecular-weight form of Pregnancy-Specific beta 1-Glycoprotein designated PSB1G-I that had been previously isolated from maternal serum was studied by gel chromatography in guanidine hydrochloride dissociating solvent. Evidence was obtained that subunits of identical size (bonded together non-...

journal_title：Journal of reproductive immunology

authors： Griffiths BW,Godard A

更新日期：1981-06-01 00:00:00

abstract：:Thoracic duct lymphocytes from pregnant PVG rats differed markedly from similar cells collected from non-pregnant donors in their reactivity in popliteal lymph node assays performed in (PVG x DA) F1 hybrid hosts. Cells from pregnant rats failed to evoke an increase in popliteal node size commensurate with higher chall...

journal_title：Journal of reproductive immunology

authors： McCullagh P

更新日期：1981-05-01 00:00:00

abstract：:Antisera to Mason-Pfizer or Baboon Endogenous Virus possessed complement-dependent cytotoxicity for cell lines chronically infected with these viruses, with some degree of cross-reaction. When appropriately absorbed with virus-free cells, the antisera were not cytotoxic for lymphocytes of adult males but lysed lymphoc...

journal_title：Journal of reproductive immunology

authors： Thiry L,Sprecher-Goldberger S,Hard RC,Bossens M,Neuray F

更新日期：1981-03-01 00:00:00

abstract：:Phytohaemagglutinin (PHA) was employed to study the constituents of the cell membrane in X- and Y-bearing human spermatozoa. The presence of certain receptors for PHA was revealed in the equatorial region of about 50% of the spermatozoa. To determine the association of the equatorial staining by PHA with one of the su...

journal_title：Journal of reproductive immunology

authors： Hegde UC,Shastry PR,Rao SS

更新日期：1981-03-01 00:00:00

abstract：:The inhibitory effect of antilymphocyte globulin on spontaneous rosette formation by peripheral blood T cells between 10 and 21 weeks gestation was examined. No evidence was obtained from either a cross-sectional or a longitudinal study that increased rosette inhibition levels occur during early human pregnancy. Compa...

journal_title：Journal of reproductive immunology

authors： Thomson AW,Milton JI,Campbell DM,Horne CH

更新日期：1980-12-01 00:00:00

abstract：:The levels of rabbit alpha-foetoprotein (RAFP) in foetal serum, neonatal serum and amniotic fluid during gestation have been evaluated by quantitative radial immunodiffusion. RAFP attained its peak concentration on the 24th day of pregnancy in foetal serum, while in amniotic fluid peaks were observed on ;the 14th and...

journal_title：Journal of reproductive immunology

authors： Clarke LE

更新日期：1980-11-01 00:00:00

abstract：:Maternal plasma concentrations of pregnancy-associated alpha 2-glycoprotein (alpha 2-PAG) were measured in normal pregnancy and in pregnancies complicated by apparent threatened abortion, pre-eclampsia or intrauterine growth retardation (IUGR). alpha 2-PAG levels were significantly decreased in those women who spontan...

journal_title：Journal of reproductive immunology

authors： Thomson AW,Powrie JK,Horne CH

更新日期：1979-12-01 00:00:00

abstract：:The objective of these experiments was to determine the effects of neonatal thymectomy on the induction of experimental autoimmune orchitis in inbred rats of the Fischer 344 and Lewis strains. It was found that thymectomy alone in Lewis rats, and thymectomy followed by immunization with testicular extract in both Lewi...

journal_title：Journal of reproductive immunology

authors： Lipscomb HL,Gardner PJ,Sharp JG

更新日期：1979-12-01 00:00:00

abstract：:Syncytiotrophoblast microvillous plasma membrane (StMPM) preparations were obtained from human full-term placentae by previously published methods of cold saline extraction and phase centrifugation. Purity of these preparations was assessed by electron microscopy, enzyme analysis and hydroxyproline content. IgG, album...

journal_title：Journal of reproductive immunology

authors： Ogbimi AO,Johnson PM,Brown PJ,Fox H

更新日期：1979-07-01 00:00:00